KETOROLAC trometamol, 30mg/ml, 1ml, amp.

STD DINJKTRT3A1

Valid Article

Former Code(s): DINJZRU0006

The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
M01AB15
Anatomical Therapeutic Chemical Classification according to WHOCC
The order of this product needs to be justified and is only acceptable under certain conditions.
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.

OC subscriptions: included in supply or field order tools (e.g. UniField)
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)
SC subscriptions: included in supply or field tools

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KETOROLAC trometamol

Therapeutic Action

Non-opioid analgesic, non-steroidal anti-inflammatory class (NSAID)

Indications

Short-term management of moderate to severe post-operative pain in adults and children over 2 years of age.

Instructions for use

Must be given by IV route intraoperatively or IM route after the intervention, as a single dose.

It may be continued for up to 48 hours when short-term NSAID treatment is necessary, and oral administration is not possible.

Prefer ibuprofen when oral administration is possible.

Remark:

For periopertaive use, IV Ketorolac is more suitable than IM diclofenac, as it does not require dilution or buffering with sodium bicarbonate, facilitating preparation and reducing associated risks. Ketorolac can be administered by IV route without additional preparation.

Precautions for Use

Do not administer by epidural or spinal route.

Not recommended in children under 2 years of age.

Contraindicated in patients with:

  • coagulopathy, major haemorrhage, ongoing bleeding, traumatic brain injury, and spinal cord injury
  • history of myocardial infarction
  • pre-existing or de novo renal failure, risk of acute kidney injury (hypovolaemia, shock)
  • ongoing peptic ulcer
  • presence of an NG tube and not being fed
  • during pregnancy
  • patients on aspirin for cardiovascular prevention

Do not combine with:

  • Other NSAIDs (e.g., aspirin, ibuprofen, or diclofenac)
  • Anticoagulants (e.g., warfarin, heparin, or clopidogrel)
  • Probenecid
  • Lithium

Do not mix in small volumes (e.g., in a syringe) with morphine, pethidine, promethazine, or hydroxyzine, as this will cause ketorolac to precipitate.

Storage

Below 25ºC - Protect from sunlight