Transport of samples: Cold chain preparation
5 Cold chain preparation
The insulated boxes available in the catalogue will keep the temperature between +2 °C and +8 °C for 2 days at an ambient temperature of 28 °C. It has not been tested at higher ambient temperatures.
5.1 Shipping at +2 °C to +8 °C with 0.6-litre ice packs
The procedure for samples that have to be sent at +2 °C to +8 °C using ice packs is as follows:
- Prepare an insulated triple-packaging box.
- Prepare the four ice packs:
- Remove them from the freezer and leave them in a +20°C location, protected from the sun.
- After 15 minutes, check the amount of liquid in the ice packs. To ensure that the ice packs are at the right temperature, they should have 5 cm of water visible in the bottom when held vertically. When the ice packs are shaken, the sound of water can be heard.
! If there is less than 5 cm of water or no water at all, the packs are too cold, and the samples might freeze early in transport !
! If there is more than 5 cm of water, the packs are too warm, and the temperature might get too high during transport ! - If the ice packs are not at the correct temperature after 15 minutes, leave them for another 15 minutes, protected from sunlight, and then check again.
- Once all four ice packs are at the correct temperature, place them in the insulated box.
- Put the samples, in their packaging, into the box.
- Close the insulated box.
6. Documentation
6.1 IATA : Category A - UN2814
Indicative examples of infectious substances included in Category A in any form unless otherwiseindicated
| UN Number and Proper Shipping Name | Micro-organism | Form |
| UN2814 Infectious substance affecting humans | Bacillus anthracis | Cultures only |
| Brucella abortus | Cultures only | |
| Brucella melitensis | Cultures only | |
| Brucella suis | Cultures only | |
| Burkholderia mallei – Pseudomonas mallei – Glanders | Cultures only | |
| Burkholderia pseudomallei – Pseudomonas pseudomallei | Cultures only | |
| Chlamydia psittaci – avian strains | Cultures only | |
| Clostridium botulinum | Cultures only | |
| Coccidioides immitis | Cultures only | |
| Coxiella burnetii | Cultures only | |
| Escherichia coli, verotoxigenic | Cultures only | |
| Francisella tularensis | Cultures only | |
| Hantavirus causing hemorrhagic fever with renal syndrome | ||
| Mycobacterium tuberculosis | Cultures only | |
| Poliovirus | Cultures only | |
| Rickettsia prowazekii | Cultures only | |
| Rickettsia rickettsii | Cultures only | |
| Shigella dysenteriae type 1 | Cultures only | |
| Dengue virus | Cultures only | |
| Rift Valley fever virus | Cultures only | |
| Crimean-Congo haemorrhagic fever virus | ||
| Omsk haemorragic fever virus | ||
| Yellow fever virus | Cultures only | |
| Kyasanur Forest disease virus | ||
| Variola virus | ||
| Tick-borne encephalitis virus | Cultures only | |
| Eastern equine encephalitis virus | Cultures only | |
| Cultures onlyVenezuelan equine encephalitis virus | Cultures only | |
| Japanese Encephalitis virus | Cultures only | |
| Russian spring-summer encephalitis virus | Cultures only | |
| Hepatitis B virus | Cultures only | |
| Human immunodeficiency virus | Cultures only | |
| Highly pathogenic avian influenza virus | Cultures only | |
| Marburg virus | ||
| West Nile virus | Cultures only | |
| Ebola virus | ||
| Flexal virus | ||
| Guanarito virus | ||
| Hantaan virus | ||
| Hendra virus | ||
| Herpes B virus | Cultures only | |
| Junin virus | ||
| Lassa virus | ||
| Machupo virus | ||
| Monkeypox virus | ||
| Nipah virus | ||
| Rabies virus | Cultures only | |
| Sabia virus | ||
| Yersinia pestis | Cultures only |
Adapted from Guidance on regulations for the transport of infectious substances 2021-2022. Geneva: World Health Organization; 2021. Licence: CCBY-NC-SA3.0IG
6.2 Sample dangerous goods declaration (DGD)
6.3 Sample donation certificate
6.4 Sample Air Waybill (AWB)
6.5 Institut Pasteur shipping label
Available at the following address:
https://www.pasteur.fr/fr/file/3157/download?token=Evu6jsP5
Regardless of the mode of transport, fill out and affix a label as above to the outer packaging of all shipments destined for the Institut Pasteur's National Reference Centers.
Sender:
- Name
- Hospital/Laboratory/Unit
- Address
- Postal code
- City
- Country
- Phone number
- Fax number
Storage conditions: choose one
- Ambient temperature
- + 4 °C
- -20 °C
Recipient:
- Institut Pasteur
- National reference laboratory of _______________________________
- For the attention of _________________________________________
- Address: already added
References
1. Guidance on regulation for the transport of infectious substances 2021-2022/WHO
https://apps.who.int/iris/handle/10665/339825
2. Exempt Human/Animal specimens shipping guidelines. Retrieved from :
https://www.cancertrials.ie/wp-content/uploads/2018/05/DHL_Exempt-Human-Animal-Specimen-Customer-2015.pdf
3. IATA document. Dangerous Goods Regulations (DGR). 62nd Edition. 2021. Retrieved from