ARTESUNATE 60mg, pwd vial + ARGININE 2%/NaHCO3 0.84% 3ml amp

STD DINJARTS6V3

Valid Article

Former Code(s): DINJARTS6V7

The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
P01BE03
Anatomical Therapeutic Chemical Classification according to WHOCC
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.

OC subscriptions: included in supply or field order tools (e.g. UniField)
SC subscriptions: included in supply or field tools
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)

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ARTESUNATE + ARGININE

Full Name

Argesun®

Therapeutic Action

Antimalarial, artemisinine derivative

Indications

Severe malaria caused by Plasmodium falciparum

Instructions for use

Two different combi-packs are available, each containing:

  • 1 powder vial of artesunate 120 mg + 1 ampoule with 6 ml sodium bicarbonate (NaHCO3) 0.84% (8.4mg/ml) and arginine2% (20 mg/ml) for reconstitution (DINJARTS1V1)
  • 1 powder vial of artesunate 60 mg + 1 ampoule with 3 ml of sodium bicarbonate (NaHCO3) 0.84% (8.4mg/ml) and arginine2% (20 mg/ml) for reconstitution (DINJARTS6V3)

This artesunate-arginine formulation eliminates the need to reconstitute and then dilute the powder separately. It simplifies and accelerates preparation and administration, reducing the risk of errors.

For instructions on reconstitution and administration, refer to Injectable Artesunate FOR SEVERE MALARIA ONLY (see related articles).

Must be given as slow IV or IM injection.

Remark: Missions should first use remaining stocks of artesunate without arginine before ordering the formulation with arginine. Having both formulations simultaneously at field level is discouraged.

Precautions for Use

Never administer by IV infusion.

Do not reconstitute the artesunate powder with water for injection; use only the diluent provided in the ampoule.

Storage

  • Below 25ºC - Protect from sunlight
  • Do not refrigerate or freeze.
  • After reconstitution, use the solution immediately.