RITONAVIR (r), 100mg, tab.
Valid Article
RITONAVIR (r)
Therapeutic Action
Antiretroviral, protease inhibitor (PI)
Indications
Booster for protease inhibitors (darunavir, lopinavir, atazanavir) in HIV infection. Not used as an antiretroviral on its own.
Combination of darunavir / ritonavir is the preferred boosted protease inhibitor option for ART if a protease inhibitor is needed.
Combinations of atazanavir + ritonavir or lopinavir + ritonavir can be used as alternatives if darunavir / ritonavir cannot be used.
Instructions for use
Ritonavir should not be used alone but in combination with other protease inhibitors.
Fixed-dose combinations (FDC) are available:
- DRV eq. 400mg base / r 50mg, tab.
- ATV 300mg / r 100mg, tab.
- LPV 40mg / r 10mg, granules, sachet
- LPV 100mg / r 25mg, tab.
- LPV 200mg / r 50mg, tab.
The 100 mg ritonavir tablet may be required to boost darunavir in patients with TB who are on protease inhibitor-based ART.
Storage
Below 25ºC