1. All Products
  2. D - Drugs
  3. ISOSORBIDE MONONITRATE, 60mg, prolonged-release, tab.
Public Pricelist

ISOSORBIDE MONONITRATE, 60mg, prolonged-release, tab.

https://unicat.msf.org/cat/product/96537
STD DORAISOS6TP

Valid Article

12.1 - Antianginal medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
C01DA14
Anatomical Therapeutic Chemical Classification according to WHOCC
PM
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
Thermosensitive codes are defined for storage and transportation temperature requirements of the products.
OC subscriptions: included in supply or field order tools (e.g. UniField)
OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)
SC subscriptions: included in supply or field tools
https://unicat.msf.org/web/image/product.template/589854/image_1920?unique=e1af746

This combination does not exist.

Add article to list

   
Create Cancel

Add Kit To Wishlist

   
Create Cancel

ISOSORBIDE MONONITRATE 60 mg prolonged release

Therapeutic Action

Vasodilator, antianginal

Extended-release formulation of isosorbide-5-mononitrate, which is released gradually over a 10-hour period.

Isosorbide mononitrate is an active metabolite of isosorbide dinitrate.

Indications

Long-term prophylaxis of angina pectoris due to coronary artery disease.

Long-term treatment of left-sided or global chronic heart failure in patients with intolerance to angiotensin-converting enzyme (ACE) inhibitors (e.g. enalapril)

Not indicated for the relief of acute angina attacks; for an acute attacks, use sublingual glyceril trinitrate tablets.

Some restricted information has been hidden. Sign in to see this information

Instructions for use

Tablets should be swallowed whole, with half a glass of water. Do not chew or crush the tablets.

Posology (for adult only): start with 30 mg (half tablet) once daily in the morning for 4 days to minimise headaches side effect, then increase to 60 mg (one tablet) once daily in the morning. If needed, the dose may be increased to 120 mg (2 tablets) once daily in the morning.

Compared to 5 mg immediate-release isosorbide taken multiple times a day, the prolonged-release formulation reduces the risk of tolerance and increases patient compliance.

Precautions for Use

To be used in adults only.

Contraindications:

  • Hypotension
  • Obstructive myocardiopathy (e.g., aortic or mitral stenosis, constrictive pericarditis)
  • Intracranial hypertension
  • Neurologic injury
  • Severe anaemia

Most common side effects: headache, dizziness, fatigue, nausea, tachycardia.

Storage

Below 25ºC - Protect from sunlight - Protect from humidity